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Impact of Yo-Yo Sleep on Cardiometabolic Health
Sponsor: Columbia University
Summary
The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance and cardiometabolic risk. A secondary goal of this research is to determine if maintaining a constant midpoint of sleep while undergoing intermittent short sleep, leads to better outcomes than intermittent short sleep with a 2-hour delay in sleep midpoint. The aims of this research will be tested in the context of a 3-group, parallel-arm, outpatient intervention of 4 weeks in duration, in young-to-middle-aged adults (aged 18-49 years).
Key Details
Gender
All
Age Range
18 Years - 49 Years
Study Type
INTERVENTIONAL
Enrollment
72
Start Date
2023-09-22
Completion Date
2028-06
Last Updated
2025-05-14
Healthy Volunteers
Yes
Conditions
Interventions
Intermittent Short Sleep (ISS)
Restricted sleep duration of \<5.5 h/night for 5 nights (SR) followed by 2 nights of 9.5 hours of time in bed (TIB) (recover sleep) each week.
Social Jetlag (SJL)
2-hour delayed sleep timing.
Sustained Adequate Sleep (SAS)
Goal of ≥7 hours of sleep/night with 8 hours of time in bed (TIB).
Locations (1)
Columbia University Irving Medical Center
New York, New York, United States