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Impact of Gonadotoxic Therapies on Fertility
Sponsor: Michael von Wolff
Summary
The goal of this observational study is to learn how gonadotoxic treatments (chemotherapies, radiotherapies or immunotherapies) affect the fertility status of participants with cancer. The main questions it aims to answer are: * in females, if cancer therapies reduce the Anti-Müllerian hormone (AMH) concentration (ovarian reserve); * in males, if cancer therapies reduce sperm concentration (sperm quality).
Official title: FertiTOX - Platform for Fertility Related Gonadotoxicity of Cancer Therapies
Key Details
Gender
All
Age Range
14 Years - 50 Years
Study Type
OBSERVATIONAL
Enrollment
7000
Start Date
2023-12-01
Completion Date
2038-12-31
Last Updated
2024-06-03
Healthy Volunteers
No
Conditions
Interventions
Blood samples for analysis
Test hormone levels in blood
Sperm samples for analysis
Spermiogram
Satisfaction evaluation
Participant satisfaction assessment
Quality of Life questionnaire
The World Health Organization Quality of Life Brief 26-item Version (WHOQOL-BREF)
Locations (1)
University Women's Hospital (Inselspital)
Bern, Switzerland