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COMPLETED
NCT05885750
NA

The Impact of Plant-Based Protein-rich Food Products With Varying Degree of Processing on the Human Gut Microbiome Composition and Human Metabolome

Sponsor: University of Turku

View on ClinicalTrials.gov

Summary

It is observed that replacing meat with protein-rich plant-based food products are associated with lower mortality and obesity prevention. Sources of plant proteins typically undergo several processing and refinement procedures to improve the taste and digestibility of plant-based food products. These procedures alter the chemical composition, which can impact the nutritional quality of the processed food. It is not known what is the impact of processed products on human metabolism and intestinal microbiota. Therefore, the impact of a set of plant-based protein-rich food products with varying degree of processing on the composition and function of human gut microbiome and metabolism will be assessed in a clinical intervention

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

38

Start Date

2023-04-05

Completion Date

2023-12-19

Last Updated

2026-05-07

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

Unprocessed

Participants will consume unprocessed or minimally processed commercially available plant-based protein-rich foods as meat replacement in their normal diet for one week.

BEHAVIORAL

Mildly processed

Participants will consume mildly processed commercially available plant-based protein-rich foods as meat replacement in their normal diet for one week.

BEHAVIORAL

Heavily refined

Participants will consume heavily refined processed commercially available plant-based protein-rich foods as meat replacement in their normal diet for one week.

Locations (1)

Food Sciences Unit, Department of Life Technologies, Faculty of Technology, University of Turku

Turku, Finland