Clinical Research Directory

Inclusion Criteria: 1. Adult women aged 18-65 years who plan to undergo unilateral or bilateral immediate prepectoral prothesis breast reconstruction; 2. SSM or NSM or Skin-Reducing Mastectomy for breast cancer patients or prophylactic mastectomy; 3. Tissue expander size =\<800cc, implant size =\<600cc; 4. The blood perfusion of breast skin flap was well; 5. Do not smoking in the last 4 weeks or more 6. Patients with normal expectations and mental health for breast reconstruction; 7. Signed consent to participate Exclusion Criteria: 1. Poor perfusion of breast mastectomy flap; 2. II stage breast reconstruction patients; 3. History of chest radiotherapy; 4. BMI greater than 35; 5. Patients who have not quit smoking within the last 4 weeks;