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Circulating Tumor DNA Guided Treatment Monitoring in Advanced Lung Cancer
Sponsor: Zealand University Hospital
Summary
The study is a prospective randomized interventional study including patients with advanced non-small cell lung cancer, receiving immunotherapy, with the aim of optimizing treatment monitoring. The study aims to investigate the clinical utility of liquid biopsy monitoring in order to reduce the numbers of inefficient treatments and needless toxicity - and to explore the cost-effectiveness and cost-utility of introducing liquid biopsy monitoring in daily clinical practice.
Official title: Circulating Tumor DNA Guided Treatment Monitoring in Advanced Lung Cancer - a Randomized Interventional Study
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
350
Start Date
2023-07-28
Completion Date
2032-06
Last Updated
2026-01-09
Healthy Volunteers
No
Conditions
Interventions
Circulating tumor DNA treatment monitoring
A comparison of treatment monitoring by circulating tumor DNA and CT scans (standard) in patients with newly diagnosed advanced Non-Small Cell Lung Cancer (NSCLC)
Locations (5)
Department of Clinical Oncology
Hillerød, Region H, Denmark
Department of Clinical Oncology and Palliative Care
Næstved, Region Sjælland, Denmark
Department of Clinical Oncology and Palliative Care
Roskilde, Region Sjælland, Denmark
Department of Oncology
Aalborg, Denmark
Department of Oncology
Vejle, Denmark