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Low-Intensity Mechanical Stimulation for Hematologic Malignancy Patients
Sponsor: Roswell Park Cancer Institute
Summary
This clinical trial tests the effect of low-intensity mechanical stimulation (LIMS) vibration therapy in patients with hematologic malignancies. Patients with hematologic malignancies often undergo a blood and/or bone marrow transplant (hematopoietic cell transplantation \[HCT\]) or cellular therapy. The LIMS board delivers vibrations through the bones that may stimulate bone growth and may also increase muscle activity and strength and may also increase T-cell activation in patients planning to undergo cellular therapy. LIMS vibration therapy may stop or reverse BMD loss and/or improve the development of T-cells in the body in patients with hematologic malignancies who are undergoing or may plan to undergo HCT or cellular therapies.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
75
Start Date
2023-08-14
Completion Date
2026-09-01
Last Updated
2025-12-03
Healthy Volunteers
No
Interventions
Low Intensity Vibration Therapy
Undergo LIMS vibration therapy
Dual X-ray Absorptiometry
Undergo DEXA scan
Biospecimen Collection
Undergo blood sample collection
Locations (1)
Roswell Park Comprehensive Cancer Center
Buffalo, New York, United States