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RECRUITING
NCT05893940
NA

Low-Intensity Mechanical Stimulation for Hematologic Malignancy Patients

Sponsor: Roswell Park Cancer Institute

View on ClinicalTrials.gov

Summary

This clinical trial tests the effect of low-intensity mechanical stimulation (LIMS) vibration therapy in patients with hematologic malignancies. Patients with hematologic malignancies often undergo a blood and/or bone marrow transplant (hematopoietic cell transplantation \[HCT\]) or cellular therapy. The LIMS board delivers vibrations through the bones that may stimulate bone growth and may also increase muscle activity and strength and may also increase T-cell activation in patients planning to undergo cellular therapy. LIMS vibration therapy may stop or reverse BMD loss and/or improve the development of T-cells in the body in patients with hematologic malignancies who are undergoing or may plan to undergo HCT or cellular therapies.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

75

Start Date

2023-08-14

Completion Date

2026-09-01

Last Updated

2025-12-03

Healthy Volunteers

No

Interventions

PROCEDURE

Low Intensity Vibration Therapy

Undergo LIMS vibration therapy

PROCEDURE

Dual X-ray Absorptiometry

Undergo DEXA scan

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

Locations (1)

Roswell Park Comprehensive Cancer Center

Buffalo, New York, United States