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Zinc-containing Vaginal Gel and Oral Fluconazole for Vulvovaginal Candidiasis.
Sponsor: FEMPHARMA Kft.
Summary
Vaginitis is one of the most common gynecological problems in women. Candida albicans is responsible for more than 85% of vaginal fungal infections and reinfection after standard treatment is quite common. The aim of this study is to compare the effects of a zinc-containing vaginal gel and oral fluconazole on the treatment and recurrence of vulvovaginal candidiasis (VVC). The investigator's hypothesis is that zinc-containing vaginal gel may decrease the rate of reinfection after standard treatment with oral 150 mg fluconazole.
Official title: Randomized Controlled Trial to Assess the Effectiveness of a Zinc-containing Vaginal Gel and Fluconazole on Treatment and Recurrence of Vulvovaginal Candidiasis.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2023-06-10
Completion Date
2026-04-20
Last Updated
2026-09-02
Healthy Volunteers
No
Interventions
JUVIA zinc containing vaginal gel treatment
Women receive a single oral dose of fluconazole (150mg) followed by treatment with JUVIA zinc containing vaginal gel (daily for 2 weeks and twice per week thereafter).
Fluconazole 150Mg Tab
Women receive oral fluconazole treatment with a single dose of oral fluconazole (150 mg).
Locations (1)
Dr. Secret Private Clinic
Debrecen, HB, Hungary