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ACTIVE NOT RECRUITING
NCT05899114
NA

Less Is More: Optimized Pharmacotherapy With Improved coNtinuity of CarE in hospitaLized oLder peOple

Sponsor: Radboud University Medical Center

View on ClinicalTrials.gov

Summary

The goal of this cluster randomized controlled trial is to compare transitional multidisciplinary pharmacotherapeutic care (TMPC) with usual care in patients aged 70 years or older with polypharmacy, admitted to the hospital via the emergency department for longer than 24 hours and that have an elevated risk of drug related readmissions. The primary aims of the study are: * To assess whether TMPC leads to a decrease in number of DRreAs compared to usual care during the first 30 days after index hospitalisation. * To assess whether TMPC is cost-effective Participants will receive TMPC in hospitals allocated to the intervention. TMPC will be executed by a pharmacotherapeutic team, it consists of the following four elements: * pharmacotherapeutic analysis * transitional multidisciplinary discussion * pharmacotherapeutic care interview and discussion with the patient * discharge note with the pharmacotherapeutic care plan Researchers will compare TMPC with usual care to assess the effect and cost-effectiveness of TMPC.

Key Details

Gender

All

Age Range

70 Years - Any

Study Type

INTERVENTIONAL

Enrollment

2576

Start Date

2023-06-05

Completion Date

2026-01-17

Last Updated

2025-08-11

Healthy Volunteers

No

Interventions

OTHER

Transitional Multidisciplinary Pharmacotherapeutic Care

A structured medication review with improved transitional care and multidisciplinary collaboration. TMPC consists of the following four elements: 1. A structured pharmacotherapeutic analysis 2. A transitional multidisciplinary discussion.The treating physician in the hospital will be involved. The general practitioner and community pharmacist will be consulted. 3. An interview and discussion with the patient and/or legal representative by a member of the Pharmacotherapy-team, which will be performed before the patient is discharged from the hospital. 4. A discharge note with the pharmacotherapeutic care plan. This will be sent to the community pharmacist and the general practitioner.

Locations (16)

Canisius Wilhelmina Ziekenhuis

Nijmegen, Gelderland, Netherlands

Radboudumc

Nijmegen, Gelderland, Netherlands

Amphia ziekenhuis

Breda, North Brabant, Netherlands

Catharina Ziekenhuis

Eindhoven, North Brabant, Netherlands

Amsterdam UMC - location VUMC

Amsterdam, North Holland, Netherlands

Amsterdam UMC- location AMC

Amsterdam, North Holland, Netherlands

Zaans Medisch Centrum

Zaandam, North Holland, Netherlands

Ziekenhuisgroep Twente

Almelo, Overijssel, Netherlands

Deventer Ziekenhuis

Deventer, Overijssel, Netherlands

Universitair Medisch Centrum Groningen

Groningen, Provincie Groningen, Netherlands

Leiden Universitair Medisch Centrum

Leiden, South Holland, Netherlands

Erasmus Medisch Centrum Rotterdam

Rotterdam, South Holland, Netherlands

Haga Ziekenhuis

The Hague, South Holland, Netherlands

Meander Medisch Centrum Amersfoort

Amersfoort, Utrecht, Netherlands

Diakonessenhuis

Utrecht, Utrecht, Netherlands

Universitair Medisch Centrum Utrecht

Utrecht, Utrecht, Netherlands