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Less Is More: Optimized Pharmacotherapy With Improved coNtinuity of CarE in hospitaLized oLder peOple
Sponsor: Radboud University Medical Center
Summary
The goal of this cluster randomized controlled trial is to compare transitional multidisciplinary pharmacotherapeutic care (TMPC) with usual care in patients aged 70 years or older with polypharmacy, admitted to the hospital via the emergency department for longer than 24 hours and that have an elevated risk of drug related readmissions. The primary aims of the study are: * To assess whether TMPC leads to a decrease in number of DRreAs compared to usual care during the first 30 days after index hospitalisation. * To assess whether TMPC is cost-effective Participants will receive TMPC in hospitals allocated to the intervention. TMPC will be executed by a pharmacotherapeutic team, it consists of the following four elements: * pharmacotherapeutic analysis * transitional multidisciplinary discussion * pharmacotherapeutic care interview and discussion with the patient * discharge note with the pharmacotherapeutic care plan Researchers will compare TMPC with usual care to assess the effect and cost-effectiveness of TMPC.
Key Details
Gender
All
Age Range
70 Years - Any
Study Type
INTERVENTIONAL
Enrollment
2576
Start Date
2023-06-05
Completion Date
2026-01-17
Last Updated
2025-08-11
Healthy Volunteers
No
Conditions
Interventions
Transitional Multidisciplinary Pharmacotherapeutic Care
A structured medication review with improved transitional care and multidisciplinary collaboration. TMPC consists of the following four elements: 1. A structured pharmacotherapeutic analysis 2. A transitional multidisciplinary discussion.The treating physician in the hospital will be involved. The general practitioner and community pharmacist will be consulted. 3. An interview and discussion with the patient and/or legal representative by a member of the Pharmacotherapy-team, which will be performed before the patient is discharged from the hospital. 4. A discharge note with the pharmacotherapeutic care plan. This will be sent to the community pharmacist and the general practitioner.
Locations (16)
Canisius Wilhelmina Ziekenhuis
Nijmegen, Gelderland, Netherlands
Radboudumc
Nijmegen, Gelderland, Netherlands
Amphia ziekenhuis
Breda, North Brabant, Netherlands
Catharina Ziekenhuis
Eindhoven, North Brabant, Netherlands
Amsterdam UMC - location VUMC
Amsterdam, North Holland, Netherlands
Amsterdam UMC- location AMC
Amsterdam, North Holland, Netherlands
Zaans Medisch Centrum
Zaandam, North Holland, Netherlands
Ziekenhuisgroep Twente
Almelo, Overijssel, Netherlands
Deventer Ziekenhuis
Deventer, Overijssel, Netherlands
Universitair Medisch Centrum Groningen
Groningen, Provincie Groningen, Netherlands
Leiden Universitair Medisch Centrum
Leiden, South Holland, Netherlands
Erasmus Medisch Centrum Rotterdam
Rotterdam, South Holland, Netherlands
Haga Ziekenhuis
The Hague, South Holland, Netherlands
Meander Medisch Centrum Amersfoort
Amersfoort, Utrecht, Netherlands
Diakonessenhuis
Utrecht, Utrecht, Netherlands
Universitair Medisch Centrum Utrecht
Utrecht, Utrecht, Netherlands