Clinical Research Directory

Inclusion Criteria: 1. Pathology-confirmed breast cancer patients who meet at least one of the criteria below: * Triple-negative breast cancer * Age ≤ 50 years * Male breast cancer * With personal or family history of malignancy: breast cancer, ovarian cancer, prostate cancer, pancreatic cancer, other malignancies * HER-2 negative recurrent or metastatic breast cancer * HER-2 negative high-risk breast cancer: A: Neoadjuvant phase: non-pathological complete response for triple-negative breast cancer; non-pathological complete response AND CPS+EG score ≥ 3 for hormone receptor positive breast cancer B: Adjuvant phase: ≥ pT2 or ≥ pN1 for triple-negative breast cancer; ≥ 4 lymph node metastasis for hormone receptor positive breast cancer 2. Having been or intended to be tested for germline and (or) somatic homologous recombination repair gene mutations 3. Consent to providing medical charts and homologous recombination repair gene testing results, and being cooperative for long-term follow-up Exclusion Criteria: 1. Homologous recombination repair gene testing results unavailable 2. Other factors deemed by the investigators that may sabotage the study