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Decision Making in Chronic Pain and Alcohol Use Disorder
Sponsor: Kirstin M Gatchalian
Summary
The objective of this within-subject study is to test the effects of Episodic Future Thinking (EFT) and Low-intensity Focused Ultrasound (LIFU) interventions on the pain of subjects who have chronic pain and alcohol use disorder(s).
Key Details
Gender
All
Age Range
21 Years - Any
Study Type
INTERVENTIONAL
Enrollment
4
Start Date
2024-06-28
Completion Date
2026-07-31
Last Updated
2026-09-14
Healthy Volunteers
No
Conditions
Interventions
Episodic Future Thinking
Participants will generate descriptions of vivid positive future events.
Control Episodic Thinking
Participants will generate descriptions of vivid positive past events.
Low-intensity Focused Ultrasound
A transducer device will use focused ultrasound energy to neuromodulate the insular cortex. The participant's brain will be mapped based on information from the CT and MRI scans, and the transducer will deliver brief ultrasound pulses to the insular cortex.
Sham Low-intensity Focused Ultrasound
All of the same actions done during LIFU will be performed, but the device will be inactive.
Locations (1)
Fralin Biomedical Research Institute at VTC
Roanoke, Virginia, United States