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TERMINATED
NCT05901610
NA

Decision Making in Chronic Pain and Alcohol Use Disorder

Sponsor: Kirstin M Gatchalian

View on ClinicalTrials.gov

Summary

The objective of this within-subject study is to test the effects of Episodic Future Thinking (EFT) and Low-intensity Focused Ultrasound (LIFU) interventions on the pain of subjects who have chronic pain and alcohol use disorder(s).

Key Details

Gender

All

Age Range

21 Years - Any

Study Type

INTERVENTIONAL

Enrollment

4

Start Date

2024-06-28

Completion Date

2026-07-31

Last Updated

2026-09-14

Healthy Volunteers

No

Interventions

BEHAVIORAL

Episodic Future Thinking

Participants will generate descriptions of vivid positive future events.

BEHAVIORAL

Control Episodic Thinking

Participants will generate descriptions of vivid positive past events.

DEVICE

Low-intensity Focused Ultrasound

A transducer device will use focused ultrasound energy to neuromodulate the insular cortex. The participant's brain will be mapped based on information from the CT and MRI scans, and the transducer will deliver brief ultrasound pulses to the insular cortex.

DEVICE

Sham Low-intensity Focused Ultrasound

All of the same actions done during LIFU will be performed, but the device will be inactive.

Locations (1)

Fralin Biomedical Research Institute at VTC

Roanoke, Virginia, United States