Clinical Research Directory

Inclusion Criteria: * Patients ≥55 years of age and \<70 years of age, with acute leukemia or MDS (with or without HCT-CI≥3); * Patients eligible for the transplantation of allogeneic hematopoietic stem cells; * Patients unavailable with HLA matched donors but available with haploidentical donors; * Voluntary participation in this study and signing the informed consent form. Exclusion Criteria: * Patients with the severe infections; * Pregnant or lactating women or female and male subjects of childbearing age and their spouses who are unable to secure effective contraception during the dosing period and within 90 days after the end of the dosing period. * Patients who are not eligible for hematopoietic stem cell transplantation; * Patients who are enrolled in other clinical trials within 1 month; * Patients who may not be able to complete the study for other reasons, or may be considered by the investigator not suitable to participate in the study; * Patients unable to properly understand or refusing to accept the informed consent form.