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Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)
Sponsor: University of Miami
Summary
This is a study of infertility which often occurs in men with spinal cord injury. Most men with spinal cord injury have a normal sperm count but abnormally low sperm motility - which means that the sperm does not swim well. This study will determine if a medicine given by mouth will improve sperm motility in men with spinal cord injuries. The medicine is called probenecid.
Key Details
Gender
MALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2024-01-18
Completion Date
2028-12-31
Last Updated
2026-03-02
Healthy Volunteers
No
Conditions
Interventions
Probenecid 500 Milligrams (mg)
Participants in this group will receive 500 mg of probenecid by mouth twice a day for a total of 90 days.
probenecid 250 Milligrams (mg)
Participants in this group will receive 250 mg of probenecid by mouth twice a day for a total of 90 days.
Placebo
Participants in this group will receive a placebo pill by mouth twice a day for a total of 90 days.
Locations (1)
University of Miami
Miami, Florida, United States