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RECRUITING
NCT05905419
NA

Neuroimaging of Opioid Phase (OPAL)

Sponsor: Duke University

View on ClinicalTrials.gov

Summary

The purpose of this study is to compare activity in the brains of female adults with chronic pain and/or opioid use, and healthy female adults that may help to develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.

Official title: Neurobiological Consequences of Long-Term Opioid Therapy in the Brain and Spinal Cord

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

140

Start Date

2023-06-01

Completion Date

2027-06-30

Last Updated

2025-09-04

Healthy Volunteers

Yes

Interventions

OTHER

Opioid Phase

Opioid-taking patients are assigned to take their prescribed opioid medication before ("peak" opioid phase) during 1 scan and after ("trough" opioid phase) during the other MRI scan

Locations (1)

Duke University Medical Center

Durham, North Carolina, United States