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Neuroimaging of Opioid Phase (OPAL)
Sponsor: Duke University
Summary
The purpose of this study is to compare activity in the brains of female adults with chronic pain and/or opioid use, and healthy female adults that may help to develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.
Official title: Neurobiological Consequences of Long-Term Opioid Therapy in the Brain and Spinal Cord
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
140
Start Date
2023-06-01
Completion Date
2027-06-30
Last Updated
2025-09-04
Healthy Volunteers
Yes
Conditions
Interventions
Opioid Phase
Opioid-taking patients are assigned to take their prescribed opioid medication before ("peak" opioid phase) during 1 scan and after ("trough" opioid phase) during the other MRI scan
Locations (1)
Duke University Medical Center
Durham, North Carolina, United States