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RECRUITING
NCT05906056
NA

Continuous Passive Motion Versus Heterotopic Ossification

Sponsor: University of Ioannina

View on ClinicalTrials.gov

Summary

The investigators hypothesize that Heterotopic Ossification (HO) formation can be suppressed if the application of a Continuous Passive Motion (CPM) device can be performed for a substantial amount of time. The investigators will use the following study design: a pilot study with 10 ICU patients receiving CPM and 10 matched cases which will follow a conventional physiotherapy program at the time of the conduction of the study. The comparison between the treatment and referent groups of the outcomes will prove the prophylactic power of CPM against HO.

Official title: Program of Continuous Passive Motion Exercises Against Heterotopic Ossification

Key Details

Gender

All

Age Range

15 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2023-05-12

Completion Date

2027-03-25

Last Updated

2024-12-06

Healthy Volunteers

No

Interventions

DEVICE

Continuous Passive Motion (CPM)

CPM uses machines to move a joint passively i.e. without the patient exerting any effort. A motorized device moves the joint repetitively to a set of degrees and movement speed, determined by the caregiver either a medical doctor (physiatrist or orthopedic surgeon) or a physiotherapist. Its action preserves the joint's range of motion (ROM)

OTHER

Conventional physiotherapy (PT)

Daily passive range of motion exercises (ROM) performed by the physiotherapist of the intensive care unit (ICU)

DRUG

Zoledronic Acid Injection

one dose of intravenous zoledronic acid will be administered

Locations (1)

Department of Physical and Rehabilitation Medicine

Ioannina, Epirus, Greece