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Posterior Circulation ASTRAL Prognostic Score
Sponsor: University of Thessaly
Summary
The goal of this study is to develop a prognostic score for ischemic posterior circulation strokes, based on our previous work on with the ASTRAL scores (Acute STroke Registry and Analysis of Lausanne) on overall stroke prognosis, intracranial occlusion, recanalization and stroke recurrences. The main question it aims to answer is the modified Rankin score in 3 months after the event. Participants will be patients with acute ischemic stroke of the posterior circulation with mRS priot to event \<3. All the data will be collected retrospectively from patients included in the ASTRAL registry between January 2003 and December 2021. The ASTRAL registry will be used as the derivation cohort of the score. Demographics, acute glucose, NIHSS score and acute imaging of each participant will be used from the derivation cohort in order to create an integer-based prognostic score. After internal validation, we plan to validate the score in external stroke registries to show its validity.
Official title: Pc-ASTRAL Score for the Prediction of 3 Months Functional Outcome in Acute Ischemic Stroke at the Posterior Circulation
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
2000
Start Date
2003-01-01
Completion Date
2025-11-24
Last Updated
2025-04-08
Healthy Volunteers
No
Interventions
ASTRAL prognostic score
ASTRAL prognostic score
Locations (2)
First Propedeutic Department of Internal Medicine & Stroke Unit, AHEPA University Hospital, Aristotle University of Thessaloniki
Thessaloniki, Central Macedonia, Greece
Stroke Center, Department of clinical neurosciences, Lausanne University Hospital and University of Lausanne
Lausanne, Vaud Canton, Switzerland