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Effects of Flow Magnitude on Cardiorespiratory Stability During Nasal High Flow Therapy in Preterm Infants
Sponsor: Insel Gruppe AG, University Hospital Bern
Summary
Premature babies often need help breathing for a longer period of time. Traditionally, this is done with a breathing aid called NCPAP (nasal continuous positive airway pressure). This treatment is safe and effective, but it is very time-consuming and can sometimes have side effects. In the present research project, the investigators want to find out whether another type of breathing aid called NHF (nasal high flow therapy) is just as effective for stable premature babies. The investigators suspect that NHF is just as effective, but easier to use and more comfortable.
Official title: Effects of Flow Magnitude on Cardiorespiratory Stability During Nasal High Flow Therapy in Preterm Infants (MASTER Trial)
Key Details
Gender
All
Age Range
23 Weeks - 31 Weeks
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2023-07-01
Completion Date
2026-02
Last Updated
2025-02-21
Healthy Volunteers
No
Conditions
Interventions
NHF high
Nasal high flow therapy 8L/min.
NHF low
Nasal high flow therapy 6L/min.
NCPAP
Nasal continuous positive airway pressure 6 cm H20
Locations (2)
University Medical Center of the Johannes Gutenberg-University Mainz
Mainz, Rhineland-Palatinate, Germany
Department of Pediatrics, Inselspital
Bern, Switzerland