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Flexible Reaching Control in Parkinson Disease
Sponsor: Université Catholique de Louvain
Summary
Current research and theories have highlighted that the parameters linked to movement planning, e.g. the decision to select a movement goal, and adaptation, e.g. the ability to update control dependent on a novel dynamical context, are update quickly and within an ongoing movement in the general population. In parallel, it has been suggested that the evaluation of movement costs is a function of the basal ganglia, and it is impaired in Parkinson disease (PD). Here the investigators want to test whether these mechanisms also alter the ability of patients to update control during an ongoing action. A positive result would confirm that movement-related costs and dynamical representations depend on the integrity of the basal ganglia, in contrast a negative result would indicate that the deficit in PD is more specifically related to movement initiation, which would invite one to reconsider the cause of bradykinesia in this population.
Official title: Behavioural Study of Reaching Control in Healthy Volunteers and Volunteers With Parkinson Disease in Dynamical Context
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2023-05-01
Completion Date
2027-10-31
Last Updated
2023-06-18
Healthy Volunteers
Yes
Conditions
Interventions
Reaching movements
Participants will be instructed to perform reaching movements by moving the handle of a robotic arm mounted with a virtual reality display.
Disease Assessment
Disease stage assessed by trained professionals
Locations (1)
Université catholique de Louvain
Louvain-la-Neuve, Belgium