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RECRUITING
NCT05908266

Flexible Reaching Control in Parkinson Disease

Sponsor: Université Catholique de Louvain

View on ClinicalTrials.gov

Summary

Current research and theories have highlighted that the parameters linked to movement planning, e.g. the decision to select a movement goal, and adaptation, e.g. the ability to update control dependent on a novel dynamical context, are update quickly and within an ongoing movement in the general population. In parallel, it has been suggested that the evaluation of movement costs is a function of the basal ganglia, and it is impaired in Parkinson disease (PD). Here the investigators want to test whether these mechanisms also alter the ability of patients to update control during an ongoing action. A positive result would confirm that movement-related costs and dynamical representations depend on the integrity of the basal ganglia, in contrast a negative result would indicate that the deficit in PD is more specifically related to movement initiation, which would invite one to reconsider the cause of bradykinesia in this population.

Official title: Behavioural Study of Reaching Control in Healthy Volunteers and Volunteers With Parkinson Disease in Dynamical Context

Key Details

Gender

All

Age Range

18 Years - 99 Years

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2023-05-01

Completion Date

2027-10-31

Last Updated

2023-06-18

Healthy Volunteers

Yes

Interventions

OTHER

Reaching movements

Participants will be instructed to perform reaching movements by moving the handle of a robotic arm mounted with a virtual reality display.

OTHER

Disease Assessment

Disease stage assessed by trained professionals

Locations (1)

Université catholique de Louvain

Louvain-la-Neuve, Belgium