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RECRUITING
NCT05909150
PHASE2

Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation

Sponsor: Fernando Bacal

View on ClinicalTrials.gov

Summary

The goal of this study is to evaluate if hypertonic saline solution can prevent or attenuate acute kidney injury after heart transplantation in the early postoperative phase.

Official title: Use of Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

74

Start Date

2023-11-08

Completion Date

2026-12

Last Updated

2025-03-25

Healthy Volunteers

Yes

Interventions

DRUG

Sodium chloride solution 3,5%

Patients will receive 150 mL HSS 3,5% intravenous twice daily for 3 days after heart transplantation.

DRUG

Sodium chloride solution 0,9%

Patients will receive 150 mL NS 0,9% intravenous twice daily for 3 days after heart transplantation.

Locations (1)

Heart Institute, University of São Paulo.

São Paulo, Brazil