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LEft Bundle branchArea Pacing to Avoid Pacing-induced CARdiomyopathy
Sponsor: Azienda Ospedaliero Universitaria Maggiore della Carita
Summary
LEAP-CAR will evaluate the benefit of left bundle branch area pacing (LBBAP), comparing to conventional right ventricular pacing (RVP), in preventing pacing-induced cardiomyopathy (PICM) in patients undergoing pacemaker implant for advanced (2° or 3° degree) atrioventricular block, with baseline left ventricular ejection fraction (LVEF) \>45%. LEAP-CAR is a randomized, prospective, double blind clinical trial.
Official title: LEft Bundle branchArea Pacing to Avoid Pacing-induced CARdiomyopathy: the LEAP-CAR Prospective, Randomized Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
130
Start Date
2023-06-10
Completion Date
2026-06-10
Last Updated
2024-01-30
Healthy Volunteers
No
Conditions
Interventions
Left bundle branch area pacing (LBBAP)
Pacing of the conduction system of the heart to obtain physiological activation
Right ventricular pacing (RVP)
Conventional ventricular pacing
Locations (1)
Hospital "Maggiore della Carità", Division of Cardiology
Novara, Italy