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Treatment With Endovascular Intervention for STroke Patients With Existing Disability
Sponsor: University of Cincinnati
Summary
TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability prior to their stroke.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1060
Start Date
2023-11-16
Completion Date
2028-04-15
Last Updated
2026-04-08
Healthy Volunteers
No
Conditions
Interventions
Endovascular Stroke Treatment
Patients who receive endovascular stroke treatment when they are admitted into the hospital, as determined by their clinical care team. Endovascular stroke treatment consist of catheter-based treatment for the blood clot causing the acute ischemic stroke
Medical Management
Patients who receive MMM when they are admitted into the hospital, as determined by their clinical care team. MMM may involve any combination of the following: intravenous thrombolysis, antiplatelets, anti-hypertensives, cholesterol-lowering medications, and rehabilitative care. Specifically, this treatment does not involve endovascular stroke treatment.
Locations (24)
HonorHealth
Phoenix, Arizona, United States
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, United States
University of California at Los Angeles
Los Angeles, California, United States
Standford
Palo Alto, California, United States
University of Cincinnati San Diego
San Diego, California, United States
Swedish Medical Center
Englewood, Colorado, United States
Hartford Health Hospital
Hartford, Connecticut, United States
Yale University
New Haven, Connecticut, United States
University of Miami
Miami, Florida, United States
Emory University
Atlanta, Georgia, United States
University of Chicago
Chicago, Illinois, United States
University of Louisville
Louisville, Kentucky, United States
Boston Medical Center
Boston, Massachusetts, United States
Barnes Jewish Hospital
St Louis, Missouri, United States
Icahn School of Medicine at Mount Sinai
New York, New York, United States
Columbia University
New York, New York, United States
University of Cincinnati Medical Center
Cincinnati, Ohio, United States
Providence St. Vincent Medical Center
Portland, Oregon, United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States
Baptist Memorial Hospital
Memphis, Tennessee, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States
University of Texas at Austin
Austin, Texas, United States
University of Washington
Seattle, Washington, United States
West Virginia University
Morgantown, West Virginia, United States