Clinical Research Directory

Inclusion Criteria: * age ≥ 18 years old; * Person affiliated to a social security scheme or beneficiary of such a scheme; * Person having received complete information on the organization of the research and having signed informed consent; * Person having carried out a preliminary clinical examination adapted to the research. * Patients with Cushing's syndrome (for the Cushing's Syndrome group) * Patients with possible Cushing's syndrome (for the suspected Cushing's Syndrome group) defined as response to the dexamethasone supression test with 1 mg of Dexamethasone, with a plasma cortisol assay at 8 am between 18 and 50 µg/L carried out in the 3 months preceding ; * Patients with metabolic syndrome (for the metabolic syndrome group) Exclusion Criteria: * Person having taken corticosteroid therapy for more than 3 months during the 2 years preceding inclusion; * Person having received corticosteroid therapy of shorter duration with discontinuation less than one month before inclusion; * Person having taken anticortisolic treatment for more than 3 months during the 2 years preceding inclusion; * Person with chronic liver disease; * Person with alcohol misuse, defined by a weekly consumption of more than 10 standard units; * Person with a morphotype that does not allow an MRI examination to be performed; * Woman of childbearing age who does not have an effective means of contraception; * Contraindication to performing an MRI examination. * Person referred to in Articles L. 1121-5, L. 1121-7 and L1121-8 of the French Public Health Code.