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Ultrahypofractionation and Normal Tissue Toxicity
Sponsor: Massachusetts General Hospital
Summary
This research is being done to see if proton beam radiation therapy (PBT) results in fewer changes to a participant's heart measured with MRI-imaging than conventional or "photon" radiation therapy (XRT) for participants with non-metastatic left sided breast cancer. The names of the two study groups in this research study are: * Proton Radiation Therapy (PBT) * Conventional or "Photon" Radiation Therapy (XRT)
Official title: Proton Versus Photon Ultrahypofractionated Radiation Therapy and Its Impact on Normal Tissue
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2023-08-15
Completion Date
2026-12-31
Last Updated
2025-11-13
Healthy Volunteers
No
Conditions
Interventions
Accelerated Proton Beam Radiation Therapy (PBT)
per protocol
Accelerated Photon Radiation Therapy (XRT)
per protocol
Locations (1)
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, United States