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ACTIVE NOT RECRUITING
NCT05912231
NA

Ultrahypofractionation and Normal Tissue Toxicity

Sponsor: Massachusetts General Hospital

View on ClinicalTrials.gov

Summary

This research is being done to see if proton beam radiation therapy (PBT) results in fewer changes to a participant's heart measured with MRI-imaging than conventional or "photon" radiation therapy (XRT) for participants with non-metastatic left sided breast cancer. The names of the two study groups in this research study are: * Proton Radiation Therapy (PBT) * Conventional or "Photon" Radiation Therapy (XRT)

Official title: Proton Versus Photon Ultrahypofractionated Radiation Therapy and Its Impact on Normal Tissue

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2023-08-15

Completion Date

2026-12-31

Last Updated

2025-11-13

Healthy Volunteers

No

Interventions

RADIATION

Accelerated Proton Beam Radiation Therapy (PBT)

per protocol

RADIATION

Accelerated Photon Radiation Therapy (XRT)

per protocol

Locations (1)

Massachusetts General Hospital Cancer Center

Boston, Massachusetts, United States