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Hyperpolarized 129-Xenon MRI in Fibrosing Interstitial Lung Disease
Sponsor: University of Aarhus
Summary
This project aims to investigate the potential of non-invasive imaging to identify and monitor the earliest signs and physiological effects of pulmonary fibrosis and resulting cardiac dysfunction in patients with fibrosing interstitial lung disease. Second, to evaluate baseline risk factors the progression and therapeutic responses to anti-fibrotic drugs.
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2023-10-05
Completion Date
2028-05-01
Last Updated
2025-12-09
Healthy Volunteers
No
Interventions
Hyperpolarized xenon-129 MRI
Participants will be asked to inhale the xenon-129 contrast agent according to procedure for gas administration. The success criterion of the drug is a obtained Xe MRI lung image with reasonable signal level
Locations (1)
Aarhus University, Department of Clinical Medicine, MR Research Centre
Aarhus, Denmark