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Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes
Sponsor: Anna Stanhewicz, PhD
Summary
The purpose of this investigation is to examine the mechanisms mediating vascular dysfunction in women who have had gestational diabetes and how metformin may be a valuable treatment tool to improve microvascular function in these women before the onset of disease.
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2024-09-11
Completion Date
2028-06-30
Last Updated
2025-05-13
Healthy Volunteers
Yes
Conditions
Interventions
Metformin Hydrochloride
12 weeks: 850mg metformin once daily for first 7 days then twice daily for the remaining 11 weeks.
placebo
12 weeks: placebo tablet once daily for the first 7 days then twice daily for the remaining 11 weeks.
Locations (1)
University of Iowa
Iowa City, Iowa, United States