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ENROLLING BY INVITATION
NCT05920616
NA

Comprehensive Imaging Exam of Convalesced COVID-19 Patients

Sponsor: Johns Hopkins University

View on ClinicalTrials.gov

Summary

COVID-19 is a systemic inflammatory disease involving many organs including the lungs, vascular system liver and myocardium that lead to severe pathologies. Patients with severe cardiopulmonary symptoms usually require weeks to months to fully recover. Studies of clinical and subclinical impairments of COVID-19 patients are important for medical practice and public health as well as providing pathogenic insight to the viral infection and secondary immune response. Chronic damage of vital organs and systems, and the potential long-term effects is of serious concern. In this study the investigators plan to quantify and characterize chronic consequences of COVID-19 in individuals who receive similar medical care related to disease severity and duration in a single health care system. Using state-of-the-art Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) technology, we will study the pathology in major organ systems in comparison to matched controls. The results of this study may facilitate measures to prevent, detect, and manage complications from COVID-19 infections.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

210

Start Date

2020-10-14

Completion Date

2026-10-31

Last Updated

2025-06-16

Healthy Volunteers

No

Interventions

OTHER

Magnetic Resonance Imaging

Completion of Magnetic Resonance Imaging of the brain, heart, lungs, and liver with and without contrast.

OTHER

Ultra-High Resolution Computed Tomography (CT) Scan

Completion of a high resolution CT scan of the lungs and high resolution CT of the coronary arteries.

Locations (1)

Johns Hopkins School of Medicine

Baltimore, Maryland, United States