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The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Heat Stroke
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Summary
The goal of this clinical trial is to compare the effect of high chlorine solution such as normal saline and non-high chlorine solution such as sodium lactate ringer's solution on renal function in patients with heat stroke. The main question it aims to answer is whether limiting the amount of normal saline infusion during emergency department can lower the incidence of acute kidney injury and mortality in patients with heat stroke. Participants will receive a free normal saline infusion during the emergency department according to the study design, or a restricted normal saline infusion while using sodium lactate Ringer's instead. Researchers will compare the normal saline infusion group and sodium lactate Ringer's group to see if limiting the amount of normal saline infusion during emergency department can lower the incidence of acute kidney injury and mortality in patients with heat stroke.
Official title: The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Patients With Heat Stroke
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
190
Start Date
2023-05-28
Completion Date
2026-03
Last Updated
2024-09-20
Healthy Volunteers
No
Conditions
Interventions
Normal Saline infusion and Ringer lactate infusion
The heat stroke patients will be infused with different chlorine concentrations fluid during the emergency department.
Locations (7)
YongKang First People's Hospital
Guli, Zhejiang, China
Yiwu Central Hospital
Yiwu, Zhejiang, China
Dongyang People's Hospital
Dongyang, China
The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, China
Jinhua Municipal Central Hospital
Jinhua, China
Jinhua People's Hospital
Jinhua, China
Lanxi People's Hospital
Lanxi, China