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RECRUITING
NCT05921695
NA

The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Heat Stroke

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to compare the effect of high chlorine solution such as normal saline and non-high chlorine solution such as sodium lactate ringer's solution on renal function in patients with heat stroke. The main question it aims to answer is whether limiting the amount of normal saline infusion during emergency department can lower the incidence of acute kidney injury and mortality in patients with heat stroke. Participants will receive a free normal saline infusion during the emergency department according to the study design, or a restricted normal saline infusion while using sodium lactate Ringer's instead. Researchers will compare the normal saline infusion group and sodium lactate Ringer's group to see if limiting the amount of normal saline infusion during emergency department can lower the incidence of acute kidney injury and mortality in patients with heat stroke.

Official title: The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Patients With Heat Stroke

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

190

Start Date

2023-05-28

Completion Date

2026-03

Last Updated

2024-09-20

Healthy Volunteers

No

Conditions

Interventions

DRUG

Normal Saline infusion and Ringer lactate infusion

The heat stroke patients will be infused with different chlorine concentrations fluid during the emergency department.

Locations (7)

YongKang First People's Hospital

Guli, Zhejiang, China

Yiwu Central Hospital

Yiwu, Zhejiang, China

Dongyang People's Hospital

Dongyang, China

The Second Affiliated Hospital of Zhejiang University School of Medicine

Hangzhou, China

Jinhua Municipal Central Hospital

Jinhua, China

Jinhua People's Hospital

Jinhua, China

Lanxi People's Hospital

Lanxi, China