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Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling-Establish Reliably Electrophysiological Readouts From Human-induced Pluripotent Stem Cells (hiPSCs)-Derived Cerebral Organoids and Surgically Dissected Human Live Brains
Sponsor: National Taiwan University Hospital
Summary
The research aims to establish a big database of multiple kinds of brain tissues and prove the relevance of human brain tissue models and hiPSCs-derived organoid models.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
500
Start Date
2023-05-01
Completion Date
2026-12-31
Last Updated
2024-08-21
Healthy Volunteers
No
Conditions
Interventions
Electrophysiological system
Electrophysiological system is used for examining voltage variation in biological samples. And multiphoton microscopy is a common type of nonlinear optical microscope.
Multiphoton microscope
Multiphoton microscope acquires high-resolution image based on nonlinear optics and can be used for detect biological specimens.
Locations (1)
Department of Surgery, National Taiwan University Hospital and College of Medicine, National Taiwan University
Taipei, Taiwan