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RECRUITING
NCT05922514

A Clinical Registry of Spontaneous Intracranial Hypotension

Sponsor: Mayo Clinic

View on ClinicalTrials.gov

Summary

The purpose of this research is to determine the efficacy of paraspinal vein embolization for treatment of digital subtraction myelography (DSM) or CT myelography (CTM) confirmed cerebrospinal fluid (CSF)-venous fistulas so that researchers can inform the development and design of future clinical trials of this technique.

Official title: Spontaneous Intracranial Hypotension Registry

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2023-06-18

Completion Date

2026-07

Last Updated

2025-12-03

Healthy Volunteers

No

Interventions

PROCEDURE

Transvenous Embolization of Cerebrospinal Fluid-Venous Fistula

Transvenous embolization of a cerebrospinal fluid-venous fistula performed via percutaneous venous access under fluoroscopic guidance. The procedure involves catheterization of the paraspinal or epidural venous system draining the fistula and delivery of an embolic agent to occlude the pathological venous outflow and eliminate CSF egress. The goal is to achieve durable fistula occlusion and resolution of spontaneous intracranial hypotension symptoms.

Locations (1)

Mayo Clinic Minnesota

Rochester, Minnesota, United States