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LISH Trial for the Hepatic Flexure and Proximal Transverse Colon Cancer
Sponsor: Zhejiang University
Summary
The goal of this clinical trial is to compare the long-term outcomes of Laparoscopic Ileocecal-Sparing Right Hemicolectomy(LISH) compared to traditional laparoscopic right hemicolectomy(TRH) in the treatment of hepatic flexure colon cancer and proximal transverse colon cancer.
Official title: Laparoscopic Ileocecal-Sparing Right Hemicolectomy for Cancer of the Hepatic Flexure and Proximal Transverse Colon -- A Prospective, Multicenter Randomized Control Clinical Trial
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
568
Start Date
2023-05-14
Completion Date
2031-05-14
Last Updated
2026-01-27
Healthy Volunteers
No
Interventions
LISH （Laparoscopic Ileocecal-Sparing Right Hemicolectomy）
Preserve the ileocolic blood vessels, and perform dissection of lymph node groups 203, 202, and 201d along the root of ICV(Ileocolic artery)/ICA(Ileocolic vein). Group 201d lymph nodes are defined as the distal lymph nodes of the ileocolic vessels (colonic branch). Use an intracavitary cutting and sealing device to transect the proximal colon along the predetermined margin, and transect the transverse colon at 10cm distal to the tumor. Perform ileocecal-transverse colonic anastomosis.
TRH（Traditional Laparoscopic Right Hemicolectomy）
Transect the root of the ileocolic vessels and perform dissection of lymph node groups 203, 202, and 201; sever the roots of the right colic and middle colic vessels, and clear the surrounding lymphoadipose tissue (lymph node groups 211/212/213 and 221/222/223). Transect the transverse colon 10cm distal to the tumor and cut the terminal ileum 10cm from the ileocecal junction. Perform ileum-to-transverse colon anastomosis.
Locations (29)
the First Affiliated Hospital of Bengbu Medical Collage
Bengbu, Anhui, China
Beijing Cancer Hospital
Beijing, Beijing Municipality, China
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China
Cancer Hospital Academy of medicine Scenice
Beijing, Beijing Municipality, China
the First Affiliated Hospital of Chongqing Medical Collage
Chongqing, Chongqing Municipality, China
Fujian Cancer Hospital
Fuzhou, Fujian, China
Fujian Hospital Medical Union University
Fuzhou, Fujian, China
The First Affiliated Hospital of Xiamen University
Xiamen, Fujian, China
Guangdong Second Provincial General Hospital
Guangzhou, Guangdong, China
The Sixth Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China
Union Hospital, Tongji Medical College, Huazhong University of Science and Technolog
Wuhan, Hubei, China
People's Hospital of Hunan Province
Changsha, Hunan, China
Jiangsu province hospital
Nanjing, Jiangsu, China
Nanjing Drum Tower Hospital
Nanjing, Jiangsu, China
The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China
Shandong Cancer Hospital
Jinan, Shandong, China
The Affiliated Hospital of Qingdao University
Qingdao, Shandong, China
Changhai Hospital of Shanghai
Shanghai, Shanghai Municipality, China
Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality, China
Ruijin Hospital Affiliated of The Shanghai Jiao Tong University Medical School
Shanghai, Shanghai Municipality, China
The first affiliated hospital of xi'an jiaotong university
Xi’an, Shanxi, China
West China Hospital of Sichuang University
Chengdu, Sichuan, China
The Cancer Hospital Affiliated of The Xingjiang University Medical School
Xinjiang, Xinjiang, China
Yunnan Cancer Hospital
Kunming, Yunnan, China
Second Affiliated Hospital Zhejiang University College of Medicine
Hangzhou, Zhejiang, China
Sir Run Run Shaw Hospital, Zhejiang University School of medicien
Hangzhou, Zhejiang, China
Zhejiang Cancer Hospital
Hangzhou, Zhejiang, China
Jinhua Municipal Central Hospital
Jinhua, Zhejiang, China
Ningbo No.2 Hospital
Ningbo, Zhejiang, China