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Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial
Sponsor: University of Pennsylvania
Summary
Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial (DECLARE) is a multi-center, outcome-masked, randomized clinical trial. The purpose of this study is to compare glaucoma drainage device implantation in the anterior chamber (front part of the eye) and sulcus (small space between iris and front chamber of the eye) in efforts to minimize cell loss in the eye.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
226
Start Date
2023-07-11
Completion Date
2027-12
Last Updated
2025-06-27
Healthy Volunteers
No
Conditions
Interventions
Sulcus tube placement
GDD implantation surgery with tube placement in the ciliary sulcus
Anterior chamber (AC) tube placement
GDD implantation surgery with tube placement in the anterior chamber
Locations (8)
University of California San Francisco
San Francisco, California, United States
Diablo Eye Associates
Walnut Creek, California, United States
Bascom Palmer Eye Institute
Miami, Florida, United States
Wilmer Eye Institute, Johns Hopkins University
Baltimore, Maryland, United States
Massachusetts Eye and Ear
Boston, Massachusetts, United States
University of Buffalo/State University of New York
Buffalo, New York, United States
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
Prism Eye Institute, University of Toronto
Toronto, Canada