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Aspirin for Postpartum Patients With Preeclampsia
Sponsor: MemorialCare Health System
Summary
The purpose of this research study is to evaluate the effect of low-dose aspirin on recovery from severe preeclampsia (a high blood pressure disorder of pregnancy) among women who have given birth. We hypothesize that taking aspirin for the first week after giving birth will enhance recovery from preeclampsia by decreasing the levels of a protein called soluble fms-like tyrosine kinase (sFlt-1), which is thought to be a main contributor to the development of preeclampsia, and speeding up return to a normal blood pressure.
Official title: Acetylsalicylic Acid for Postpartum Preeclampsia: A Pilot Randomized Trial
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
86
Start Date
2023-07-26
Completion Date
2026-12
Last Updated
2025-06-06
Healthy Volunteers
No
Conditions
Interventions
Aspirin 81Mg Ec Tab
Aspirin 81 mg 1 tablet by mouth. Participants randomized to receive aspirin in addition to standard blood pressure management will receive the study medication nightly at 20:00, with first dose initiated within 24 hours of delivery.
Locations (1)
Miller Children's and Women's Hospital, Long Beach/MemorialCare Long Beach
Long Beach, California, United States