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Circulating Tumor DNA Collection From Patients With High Grade Gliomas
Sponsor: University Health Network, Toronto
Summary
Improved outcomes for high-grade gliomas (HGG) require advances in our ability to monitor changes to tumour biology using non-surgical approaches. "Liquid biopsy" is a term used to describe a technique whereby tumour DNA, which has been shed off and then circulates through the blood stream, is detected and analyzed. Our goal is to develop a new type of liquid biopsy that is suitable for primary brain tumours that uses a method that is highly sensitive and allows for ongoing analysis of these tumours.
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
70
Start Date
2022-09-02
Completion Date
2027-09-30
Last Updated
2026-03-05
Healthy Volunteers
No
Conditions
Interventions
Radiotherapy as per standard of care
Adjuvant Radiotherapy +/- systemic therapy as per standard of care
Locations (1)
University Health Network
Toronto, Ontario, Canada