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RECRUITING
NCT05930899

Translational-Omics in Aortic Stenosis (TOmAS) Biobank

Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

View on ClinicalTrials.gov

Summary

The objective of the TOmAS Biobank is the conservation of biological material (plasma, saliva, and tissue explanted during surgery), genetic material (DNA, RNA, etc.), and clinical data ("material/data") collected from patients with cardiovascular diseases (CVD) as well as from control participants, in order to allow future studies evaluating novel proteomic, transcriptomic and epigenomic markers (as well as other emerging -omic technologies) for CVD (i.e. aortic stenosis, cardiomyopathy, myorcardial infarction, etc). The study of physiological and genetic factors will allow for the discovery of new genomic and other -omic (including proteomic, transcriptomic and epigenomic) biomarkers associated with CVD which will lead to an improved understanding of the underlying biology of CVD and may provide future insights into the prevention and treatment of this type of disease.

Key Details

Gender

All

Age Range

19 Years - Any

Study Type

OBSERVATIONAL

Enrollment

10000

Start Date

2017-10-12

Completion Date

2040-01-01

Last Updated

2024-11-20

Healthy Volunteers

Yes

Interventions

OTHER

Genetics

TOmAS is a biobank and all patients will be genotyped

Locations (2)

Montreal General Hospital

Montreal, Quebec, Canada

Royal Victoria Hospital

Montreal, Quebec, Canada