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Randomized Comparison of Skeletonized Versus Pedicled Left Internal Thoracic Artery
Sponsor: Medical University Innsbruck
Summary
Internal thoracic arteries can be harvested in skeletonized or pedicled technique. Latest research has posed a potential adverse effect of skeletonizing the internal thoracic arteries on graft patency rates and clinical outcome. Prospective, randomized, multi-centre trials are necessary to investigate the impact of harvesting technique of left internal thoracic artery (LITA) on graft patency rates and clinical outcome after coronary artery bypass grafting. The HARVITA trial compares skeletonized and pedicled harvesting technique of LITA regarding graft patency rates and patient survival.
Official title: Randomized Comparison of HARVesting the Left Internal Thoracic Artery in a Skeletonized Versus Pedicled Technique: the HARVITA Trial
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
1350
Start Date
2024-03-12
Completion Date
2031-10-01
Last Updated
2024-03-15
Healthy Volunteers
No
Conditions
Interventions
skeletonized harvesting technique
In patients who are randomized to this treatment arm, the left internal thoracic artery will be harvested in skeletonized technique. Thereby, only the artery itself is harvested.
pedicled harvesting technique
In patients who are randomized to this treatment arm, the left internal thoracic artery will be harvested in pedicled technique. Thereby, the artery will be harvested together with the accompanying veins, the endothoracic fascia and fatty tissue in order to create an 1-2 cm broad pedicle.
Locations (8)
Medical University of Graz
Graz, Austria
Medical University of Innsbruck
Innsbruck, Austria
Medical University of Vienna
Vienna, Austria
University of Duisburg-Essen
Essen, Germany
University of Freiburg
Freiburg im Breisgau, Germany
University Hospital Gießen
Giessen, Germany
University of Jena
Jena, Germany
University Hospital Bern
Bern, Switzerland