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Effects of Novel E-cigarette Constituents on Adults TCORS 3.0
Sponsor: Yale University
Summary
This study is an examination of the influence of cooling components of WS-3, WS-23, and menthol on the appeal and addiction potential of nicotine-containing e-liquids among adults.
Official title: Examining Appeal and Addiction Potential of Novel E-cigarette Constituents Among Adults
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
66
Start Date
2025-06-20
Completion Date
2026-05
Last Updated
2025-12-26
Healthy Volunteers
No
Conditions
Interventions
E-liquid coolant (No WS-3) for non-menthol (1)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants without WS-3.
E-liquid coolant (No WS-3) for low (0.1%) menthol (1)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants without WS-3.
E-liquid coolant (No WS-3) for high (2.0%) menthol (1)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants without WS-3.
E-liquid coolant (Low [0.1%] WS-3) for non-menthol (2)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-3 concentration.
E-liquid coolant (Low [0.1%] WS-3) for low (0.1%) menthol (2)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-3 concentration.
E-liquid coolant (Low [0.1%] WS-3) for high (2.0%) menthol (2)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-3 concentration.
E-liquid coolant (High [2.0%] WS-3) for non-menthol (3)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-3 concentration.
E-liquid coolant (High [2.0%] WS-3) for low (0.1%) menthol (3)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-3 concentration.
E-liquid coolant (High [2.0%] WS-3) for high (2.0%) menthol (3)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-3 concentration.
E-liquid coolant (Low [0.1%] WS-23) for non-menthol (4)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-23 concentration.
E-liquid coolant (Low [0.1%] WS-23) for low (0.1%) menthol (4)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-23 concentration.
E-liquid coolant (Low [0.1%] WS-23) for high (2.0%) menthol (4)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with low WS-23 concentration.
E-liquid coolant (High [2.0%] WS-23) for non-menthol (5)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-23 concentration.
E-liquid coolant (High [2.0%] WS-23) for low (0.1%) menthol (5)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-23 concentration.
E-liquid coolant (High [2.0%] WS-23) for high (2.0%) menthol (5)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with high WS-23 concentration.
E-liquid coolant (4% WS-23) for non-menthol (6)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with 4% WS-23 concentration.
E-liquid coolant (4% WS-23) for low (0.1%) menthol (6)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with 4% WS-23 concentration.
E-liquid coolant (4% WS-23) for high (2.0%) menthol (6)
Adult users of e-cigarette will be exposed to distinct e-liquid coolants with 4% WS-23 concentration.
Locations (1)
JB Pierce Lab
New Haven, Connecticut, United States