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Single and Combined Modality Trans-Oral Robotic Surgery in Early Oropharyngeal Cancer
Sponsor: Royal Marsden NHS Foundation Trust
Summary
Multi-centre retrospective observational cohort study with optional exploratory radiomic study (international) and prospective molecular analysis studies (UK only).
Official title: Single and Combined Modality Trans-Oral Robotic Surgery in Early Oropharyngeal Cancer: Exploring the Impact of Surgical Margins on Local Disease Recurrence: The SCORE Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
250
Start Date
2023-12-19
Completion Date
2027-08
Last Updated
2024-08-07
Healthy Volunteers
No
Conditions
Interventions
Molecular Analysis
Germline and circulating tumour DNA analysis of buccal/ blood samples and molecular analysis of primary and recurrent tumour tissue samples
Radiomic/ Morphological analysis
Radiomic analysis and assessment of morphological features of pre-operative CT/ MRI imaging in patients who have undergone TORS for primary oropharyngeal cancer.
Locations (1)
The Royal Marsden Hospital NHS Foundation Trust
London, United Kingdom