Clinical Research Directory

Inclusion Criteria: * Aged 18 to 65 * BMI 35 kg/m2 * Diagnosed T2D - according to Diabetes Canada diagnostics criteria. * Diagnosed non-T2D - according to Diabetes Canada diagnostics criteria. * Women with a negative serum pregnancy test. Exclusion Criteria: * Treatment with an oral contraceptive; * Treatment with fibrate, thiazolidinedione, insulin, or beta-blocker, drugs that affect metabolism and cannot be stopped temporarily or which have long-lasting effects; * Presence of overt cardiovascular disease, liver or renal failure or other uncontrolled medical conditions; * Any other contraindication to surgery or to temporarily suspending current medications for diabetes, lipids or hypertension; * Smoking or consumption of more than 2 alcoholic beverages per day; * Any contraindication to MRI; * A Diabetes Remission (DiaRem) score \>8 (low probability of T2D remission); * Having participated to a research study with exposure to radiation in the last two years before the start of the study; * Pregnant or breastfeeding women; * Patients weighing more than 200 kg to respect the weight and gantry limit of our MRI and PET/CT scanners. * Being allergic to eggs