Clinical Research Directory

Inclusion Criteria: * Able to provide written informed consent. * \>18 years old. * Body weight \> 50 kg. * Alcohol consumption - does not drink to excess (\>30 g/day in men, \>20 g/day in women). * Fibroscan kilopascal (kPa) between 8.5 and 13.5 within 6 months and/or a liver biopsy within the last 3 years showing a fibrosis activity score ≥ F2 and a NAS score \> 4 with a diagnosis of non alcoholic steatohepatitis (NASH) Exclusion Criteria: * (Anticipated) inability to complete the breath sampling procedure due to e.g. inability to maintain adequate ventilation unaided or claustrophobia / Inability to comply with the study procedures in the opinion of the investigator. * Participant has cirrhosis. * Participant has current hepatocellular carcinoma (HCC) or currently being treated for HCC. Those previously with/treated for and now clear of HCC can be recruited. * Participant's cause of liver disease is known to be one of alcohol abuse, hepatitis, autoimmune hepatitis, medications, haemochromatosis, alpha1 antitrypsin deficiency, Wilson disease, biliary problems. * Presence of current common cold or any other infectious disease including any recent symptoms of Covid-19. * Participant is known to be pregnant or breast feeding. * Participant with a diagnosis of chronic, active gastritis * Participant is affected by asthma, chronic obstructive pulmonary disease (COPD), and/or airway hyperactivity. * Known intolerances and/or allergies (\*) to any food containing tested compounds. For limonene, citrus fruits, and fruit juices. For benzyl alcohol, apricots, cranberries, and cocoa. For 2-pentanone cheddar cheese, ripe bananas, and defatted soybean flour. For 2-butanol cheddar cheese and yogurt. For nonanal, apple, avocado, black currants, cooked beef, cucumber, fish, grapefruit, lemon, lime, mandarin, orange, and peach.