Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Long-term Follow-up Trial of Patients Previously Treated With Imlifidase Prior to Kidney Transplantation and a Non-comparative Transplanted Patient Group
Sponsor: Hansa Biopharma AB
Summary
A prospective, post-authorisation long-term follow-up trial of patients previously treated with imlifidase prior to kidney transplantation, including a non-comparative concurrent reference cohort.
Official title: A Prospective, Post-authorisation Long-term Follow-up Trial of Patients Previously Treated With Imlifidase Prior to Kidney Transplantation, Including a Non-comparative Concurrent Reference Cohort
Key Details
Gender
All
Age Range
19 Years - 76 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2023-07-03
Completion Date
2030-04-30
Last Updated
2026-01-26
Healthy Volunteers
No
Conditions
Interventions
Imlifidase administered in the 20-HMedIdeS-19 (PAES) study
Imlifidase is an immunoglobulin G (IgG)-degrading enzyme of Streptococcus pyogenes that is highly selective towards IgG. The cleavage of IgG generates one F(ab')2- and one homodimeric Fc-fragment and efficiently neutralizes Fc-mediated activities of IgG.
Best available treatment administered in the 20-HMedIdeS-19 (PAES) study
Normal transplantation routine Transplantation and pre- and post-transplantation therapies in accordance with the clinic's normal transplantation routine.
Locations (13)
Medizinische Universitaet Wien
Vienna, Austria
Nephrology Clinic Vídeňská 1958/9
Prague, Czechia
Centre Hospitalier Universitaire (CHU) de Rouen - Hôpital de Bois-Guillaume
Bois-Guillaume, Normandy, France
Hôpital Necker - Enfants Malades
Paris, France
Azienda Ospedaliera di Padova
Padova, Italy
Leiden University Medical Center
Leiden, Netherlands
Erasmus University Medical Center
Rotterdam, Netherlands
Hospital Del Mar, Servicio de Nefrología
Barcelona, Spain
Hospital Universitario del Vall d´Hebron
Barcelona, Spain
Unidad de Trasplante Renal
Barcelona, Spain
Hospital Universitario 12 De Octubre
Madrid, Spain
Karolinska University Hospital,
Huddinge, Stockholm County, Sweden
Uppsala University Hospital
Uppsala, Sweden