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OBS'CEREVANCE: French Cohort of Pediatric Autoimmune Cytopenia
Sponsor: University Hospital, Bordeaux
Summary
From 2004, OBS'CEREVANCE is a national real-world prospective clinical cohort of patients with auto-immune cytopenia of pediatric-onset : Immune thrombocytopenia (ITP), Autoimmune Hemolytic anemia (AIHA), or Evans syndrome (all bi or tri cytopenias). Thanks to the collaboration of the 30 French pediatric hematologic centers, this cohort supports all of the Rare Disease Centre CEREVANCE (Centre de Référence National des Cytopénies Auto-Immunes de l'Enfant) missions for care, education and research. Specifically, this original unbiased database allows to describe the long-term health of adult patients, to identify the heterogenous genetic underlying pathophysiologic contexts, and to study the benefit-risk balance of treatments, including the growing development of targeted therapies.
Official title: "French National Cohort of Patients With Pediatric-onset of Autoimmune Cytopenia (OBS'CEREVANCE Cohort)"
Key Details
Gender
All
Age Range
Any - 17 Years
Study Type
OBSERVATIONAL
Enrollment
3500
Start Date
2010-09-01
Completion Date
2029-12-31
Last Updated
2023-07-10
Healthy Volunteers
No
Interventions
data collection
description of the long-term health of adult patients, identification of the heterogenous genetic underlying pathophysiologic contexts, study of the benefit-risk balance of treatments, including the growing development of targeted therapies.
Locations (9)
CHU Amiens Picardie Service d' Onco-Immuno-Hématologie Pédiatrique
Amiens, France
CHU d'Angers Unité d'Hémato-Oncologie Pédiatrique
Angers, France
BESANCON CHU de Besançon Hôpital Jean MINJOZ Unité d'Hémato-Oncologie Pédiatrique, Pédiatrie 1
Besançon, France
CHU de Bordeaux - Unité d'Hématologie et d'Oncologie pédiatrique
Bordeaux, France
CHU BREST Hôpital Morvan Unité d'Onco-Hématologie
Brest, France
CHU de Caen Unité d'Onco-Hématologie
Caen, France
CHU de Clermont Ferrand
Clermont-Ferrand, France
APHP Hôpital Bicêtre Service de Pédiatrie générale
Paris, France
CH de Cornouaille Service de Pédiatrie
Quimper, France