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Ketogenic Diet Compliance in Patients Undergoing Radiotherapy for Pelvic Cancers
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Summary
Patients with locally advanced non-metastatic adenocarcinoma of the rectum undergoing chemoradiation therapy will be assigned to 2 groups: * the intervention group will be prescribed an individualized ketogenic eating plan to be followed throughout the treatment period * the control group will be prescribed a diet therapy plan treatment following the international guidelines of clinical nutrition, also to be followed during treatment
Official title: Compliance With Ketogenic Diet in Patients Undergoing Radiotherapy for Pelvic Cancers: a Prospective, Randomized, Mono-centric Study
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
194
Start Date
2024-06-10
Completion Date
2027-12
Last Updated
2025-09-05
Healthy Volunteers
No
Conditions
Interventions
Ketogenic Diet
In the group of intervention is prescribed a ketogenic diet plan characterized by the following composition: carbohydrates \< 30g/day, 1.2g-1.5g protein/kg/day and lipids \> 65%. This diet will be followed during the period of treatment with chemo-radiotherapy (5 weeks)
Standard Diet
The control group (SD) will follow the Mediterranean diet pattern based on ESPEN guidelines (carbohydrates 45-55%, protein 15-20% and lipids 30-35%).
Locations (1)
Fondazione Policlinico Universitario Agostino Gemelli, IRCCS
Rome, Italy