Clinical Research Directory

Inclusion Criteria: 1. Patient with a diagnosis of moderate to severe chronic plaque psoriasis documented in the medical record, 2. Disease diagnosis \> 6 months (regardless of severity at diagnosis) 3. Involvement of at least one of the following areas: nails, scalp, genital, palmoplantar (non-pustular) 4. Indication for treatment by IL-23 inhibitor. Tildrakizumab must be the selected IL-23 inhibitor therapy prior to enrolling the patient in the study. Patients who have previously received previous treatment by IL-23 inhibitors may be included. 5. Patient 18 years of age or older at the inclusion visit 6. French social security beneficiary Exclusion Criteria: 1. Patient unable to comply with study requirements (i.e.complete study questionnaires) 2. Patient who, in the opinion of the investigator, should not participate in the study. This opinion should be documented in the patient's record. 3. Patient included in an interventional clinical trial at inclusion. 4. Vulnerable patient or patient under court protection 5. Patients with known hypersensitivity to IL-23 inhibitors 6. Patients with HIV or active HBV or HCV infection at the time of inclusion 7. Patient with a history of untreated latent tuberculosis or active tuberculosis at inclusion 8. Patient with any other serious active infection present at inclusion that contraindicates IL23 inhibitors use. 9. Pregnant or lactating woman