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RECRUITING
NCT05938972

Real Life Study of Biologicals in Patients With Severe CRSwNP

Sponsor: University Hospital, Ghent

View on ClinicalTrials.gov

Summary

This study is a pragmatic, real-life, observational study recruiting adult patients with chronic rhinosinusitis with nasal polyposis who are eligible to start biologicals as standard treatment. The aim of this study is to observe the long-term outcomes of biologicals in CRSwNP patients with or without comorbid asthma in 'real life'. Moreover, the investigators will gain insight into the mechanisms of biologicals in the local and systemic immunity of these patients and investigate novel local and systemic biomarkers and predictors of response.

Official title: Real Life Study Assessing Long Term Outcomes and Predictive Factors of Response to Biologicals in Patients With Severe CRSwNP and/or Severe Allergic and/or Eosinophilic Asthma

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

180

Start Date

2022-03-01

Completion Date

2030-12-31

Last Updated

2024-04-15

Healthy Volunteers

No

Interventions

BIOLOGICAL

Mepolizumab

Monoclonal antibodies

Locations (1)

Ghent University Hospital

Ghent, Belgium