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Real Life Study of Biologicals in Patients With Severe CRSwNP
Sponsor: University Hospital, Ghent
Summary
This study is a pragmatic, real-life, observational study recruiting adult patients with chronic rhinosinusitis with nasal polyposis who are eligible to start biologicals as standard treatment. The aim of this study is to observe the long-term outcomes of biologicals in CRSwNP patients with or without comorbid asthma in 'real life'. Moreover, the investigators will gain insight into the mechanisms of biologicals in the local and systemic immunity of these patients and investigate novel local and systemic biomarkers and predictors of response.
Official title: Real Life Study Assessing Long Term Outcomes and Predictive Factors of Response to Biologicals in Patients With Severe CRSwNP and/or Severe Allergic and/or Eosinophilic Asthma
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
180
Start Date
2022-03-01
Completion Date
2030-12-31
Last Updated
2024-04-15
Healthy Volunteers
No
Conditions
Interventions
Mepolizumab
Monoclonal antibodies
Locations (1)
Ghent University Hospital
Ghent, Belgium