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RECRUITING
NCT05945602

Neurophysiologic Biomarkers for Cognitive Rehabilitation

Sponsor: VA Office of Research and Development

View on ClinicalTrials.gov

Summary

Cognitive symptoms of schizophrenia interfere with daily life-from managing self-care, to more complex tasks like taking medications and living independently. Unfortunately, these cognitive symptoms are not corrected by 'standard of care' treatments (antipsychotic medications), although some schizophrenia patients may experience modest clinical and cognitive benefits from cognitive remediation. To enhance the clinical impact of cognitive remediation and other rehabilitative interventions for Veterans living with chronic psychosis, this study will develop novel brain-based tools to help identify those Veterans who are most likely to benefit from pro-cognitive therapies. These studies may advance predictive algorithms that improve functional outcomes and life quality in Veterans with schizophrenia.

Official title: Optimization of Neurophysiologic Biomarkers for Rehabilitation Interventions in Veterans With Chronic Psychosis

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

OBSERVATIONAL

Enrollment

80

Start Date

2023-10-01

Completion Date

2028-09-30

Last Updated

2025-10-09

Healthy Volunteers

Yes

Interventions

OTHER

Neurophysiologic Biomarker Assessments

Non-invasive electroencephalography will be recorded to derive neurophysiologic biomarkers.

Locations (1)

VA San Diego Healthcare System, San Diego, CA

San Diego, California, United States