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RECRUITING
NCT05946785
EARLY_PHASE1

Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

Sponsor: Anna Stanhewicz, PhD

View on ClinicalTrials.gov

Summary

The purpose of this investigation is to examine the role of oxidative stress in aberrant microvascular function in otherwise healthy women with a history of GDM.

Official title: Role of Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

Key Details

Gender

FEMALE

Age Range

18 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

28

Start Date

2023-07-01

Completion Date

2027-06-01

Last Updated

2025-05-13

Healthy Volunteers

Yes

Interventions

DRUG

Acetylcholine

acetylcholine is perfused at 10 ascending concentrations (10\^-10M - 10\^-1 M) for 5 minutes each

DRUG

insulin aspart

insulin aspart is perfused at 5 ascending concentrations (10\^-8M - 10\^-4 M) for 10 minutes each

Locations (1)

University of Iowa

Iowa City, Iowa, United States