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RECRUITING
NCT05950594
PHASE2

IVIM & OLINK in Sarcoma

Sponsor: University Health Network, Toronto

View on ClinicalTrials.gov

Summary

The hypoxia \> metastasis axis suggests that a DWI-based biomarker of hypoxia incorporating IVIM may be able to predict metastasis in STS patients, ultimately enabling stratification for personalized treatments at the time of diagnostic (MR) imaging, without adding an excessive burden to the patient or clinical workflow (typical DWI/IVIM sequences can be acquired acquired in approximately 5 minutes).

Official title: Prospective Study of Image and Blood-derived Biomarkers to Predict Metastasis in Soft-tissue Sarcomas

Key Details

Gender

All

Age Range

18 Years - 100 Years

Study Type

INTERVENTIONAL

Enrollment

145

Start Date

2024-03-05

Completion Date

2027-11-30

Last Updated

2026-03-16

Healthy Volunteers

No

Interventions

RADIATION

Radiotherapy

Standard of care pre-operative radiotherapy

OTHER

Surgery

Standard of care definitive surgery

Locations (1)

University Health Network

Toronto, Ontario, Canada