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ACTIVE NOT RECRUITING
NCT05955664
NA

Evaluation of Diffusion Tensor Imaging and High Frequency 3D Endovaginal Ultrasound

Sponsor: University Hospitals of North Midlands NHS Trust

View on ClinicalTrials.gov

Summary

To assess the feasibility of a novel MRI technique- diffusion tensor imaging with fibre tracking in understanding the anatomy of the pelvic floor and levator ani muscle injury. To compare this novel MRI technique with endocavity ultrasound in assessment of pelvic floor anatomy and deficiencies in patients with pelvic floor problems.

Official title: Evaluation of Diffusion Tensor Imaging and High Frequency 3D Endovaginal Ultrasound (EVUS) in Understanding the Anatomy of the Pelvic Floor and Levator Ani Muscle Injury.

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2021-04-12

Completion Date

2025-12-30

Last Updated

2025-07-03

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

MRI indlcuding DTI

A novel technique in MR imaging, which allows tracking of the pelvic floor muscle fibers, Diffusion Tensor Imaging (DTI) will be performed in addition to the standard scanning protocol. We think that MRI with DTI is superior to routine MRI in visualization of LAM.

DIAGNOSTIC_TEST

Pelvic floor ultrasound.

The patient will be scanned in a supine position and the probe is inserted into the vagina in the neutral position to avoid excessive pressure on surrounding structures to avoid distortion of the anatomy. The 3D data automatic acquisition takes approximately 70 seconds. The analysis of the ultrasound images will be performed on the Trust computers by Radiologists experienced in pelvic floor ultrasound. Participant will be asked to complete a VAS score for the US.

Locations (1)

University Hospital of North Midlands

Stoke-on-Trent, Staffordshire, United Kingdom