Clinical Research Directory
Browse clinical research sites, groups, and studies.
Breast Cancer Exercise Intervention Study
Sponsor: National Cancer Centre, Singapore
Summary
This is a 24-week exercise programme consisting of aerobic exercise and muscle strength training, 3 sessions per week. The first 9 sessions are supervised by physiotherapists in person, followed by 63 sessions monitored remotely (video) or supervised by trainers at ActiveSG (Sport Singapore) gyms.
Official title: Breast Cancer Exercise Intervention Study (BREXINT)
Key Details
Gender
FEMALE
Age Range
21 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
2156
Start Date
2023-07-01
Completion Date
2033-05-31
Last Updated
2025-09-05
Healthy Volunteers
No
Interventions
Exercise Programme
Aerobic exercise consists of 20-minute brisk walks or jogs (5-6 km/h) on the treadmill each session, reaching a heart rate corresponding to 50%-70% of the patient's VO2max (VO2max is determined before embarking on the exercise programme). Study participants are expected to aim for 50% VO2max at the start of the exercise programme, and gradually increasing to 70% VO2max in subsequent exercise sessions. Strength training comprises a series of circuit resistance exercises targeting the major muscle groups. Patients will perform 2-4 sets of these exercises each session, 8-10 repetitions per set. Both aerobic exercise and strength training are done in the same session. With warm-up and cool-down, each session is estimated to take up 1 hour.
Control
Usual care group.
Locations (3)
National University Hospital
Singapore, Singapore
National Cancer Centre
Singapore, Singapore
Singapore General Hospital
Singapore, Singapore