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Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG-Preschool Age
Sponsor: Children's Hospital Medical Center, Cincinnati
Summary
Individuals with Fragile X Syndrome show differences in how they understand and learn language from infancy. They frequently have lifelong delays in speech and language as well. In addition, they experience other auditory symptoms, including being very sensitive to certain sounds as well as being more sensitive than others to loud sounds. The underlying brain activity for sound perception and speech learning in Fragile X is not well understood, especially in the infant, toddler, and preschool years. This study uses behavioral assessment of speech and language abilities, neuroimaging, and hearing tests to understand how speech and hearing are different in children with Fragile X Syndrome.
Official title: Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG- Preschool Age
Key Details
Gender
All
Age Range
24 Months - 4 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2022-10-04
Completion Date
2027-03-01
Last Updated
2025-07-10
Healthy Volunteers
Yes
Conditions
Interventions
Speech discrimination
Two different speech sounds are played at the same sound intensity.
Locations (1)
Cincinnati Children'S Hospital
Cincinnati, Ohio, United States