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ACTIVE NOT RECRUITING
NCT05959083

Real World Study of Oral Upadacitinib Tablets to Assess Adverse Events and Change in Disease Activity in Adolescent and Adult Chinese Participants With Atopic Dermatitis

Sponsor: AbbVie

View on ClinicalTrials.gov

Summary

Atopic dermatitis (AD) is a skin condition that may cause a rash and itching due to inflammation of the skin. This study will assess how safe and effective upadacitinib is in treating AD in adolescent and adult Chinese participants. Upadacitinib is an approved drug for treating AD. Approximately 200 adolescent and adult participants who are prescribed upadacitinib by their physician in accordance with local label will be enrolled in China. Participants will receive upadacitinib as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed up for approximately 24 months per participant and 30 days after last treatment dose for safety data collection. There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice

Official title: A Prospective, Multi-center, Post-marketing, Observational Study to Evaluate the Safety and Effectiveness of Upadacitinib in Chinese Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (AD)

Key Details

Gender

All

Age Range

12 Years - Any

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2023-08-18

Completion Date

2026-06

Last Updated

2025-07-16

Healthy Volunteers

No

Locations (18)

Peking University Third Hospital /ID# 257722

Beijing, Beijing Municipality, China

The First Affiliated Hospital Of Fujian Medical University /ID# 257725

Fuzhou, Fujian, China

Dermatology Hospital of Southern Medical University /ID# 261862

Guangzhou, Guangdong, China

The Eighth Affiliated Hospital, Sun Yat-sen universtiy /ID# 257737

Shenzhen, Guangdong, China

People's Hospital of Henan Province /ID# 257736

Zhengzhou, Henan, China

Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 257724

Wuhan, Hubei, China

The First Hospital of China Medical University /ID# 257641

Shenyang, Liaoning, China

Second Affiliated Hospital of Xian Jiaotong University /ID# 257733

Xi'an, Shaanxi, China

Shandong Dermatological Hospital /ID# 257727

Jinan, Shandong, China

Huashan Hospital, Fudan University /ID# 256456

Shanghai, Shanghai Municipality, China

Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 257726

Shanghai, Shanghai Municipality, China

Shanghai Skin Disease Hospital /ID# 257719

Shanghai, Shanghai Municipality, China

Chengdu Second Municipal People's Hospital /ID# 257732

Chengdu, Sichuan, China

West China Hospital, Sichuan University /ID# 257720

Chengdu, Sichuan, China

Sichuan Provincial People's Hospital /ID# 263898

Chengdu, Sichuan, China

Hangzhou First People's Hospital /ID# 261867

Hangzhou, Zhejiang, China

The second affiliated hospital of Zhejiang University school of medicine /ID# 257723

Hangzhou, Zhejiang, China

Ningbo First Hospital /ID# 263884

Ningbo, Zhejiang, China